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Nature Identical Sandalwood
Odorants
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(-)-(1'S,2'R,4'R)-(Z)-beta-santalol
- Typical sandalwood scent, identical to the natural
product (Krotz & Helmchen); very strong, woody to
animal, typical sandalwood (Brunke); sandalwood, natural,
woody, milky (Chapuis)
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NA
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(+)-(1'R,2'S,4'S)-(Z)-beta-santalol
- No scent (odorless).
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Odorless
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(-)-(1'S,2'R,4'R)-
(E)-beta-santalol - Scent similar to (-)-(1'S,2'R,4'R)
-(Z)-beta-santalol but less intense (Krotz
& Helmchen); woody, medicinal, phenolic, very
weakly sandalwood (Brunke).
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NA
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(+)-(1'R,2'S,4'S)-
(E)-beta-santalol - No scent (odorless).
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Odorless
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(-)-(1'S,2'S,4'R)-(Z)-epi-beta-santalol
- not (like) sandalwood (Chapuis)
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NA
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(+)-(1'R,2'R,4'S)-(Z)-epi-beta-santalol
- weak woody (Brunke); woody, sandalwood, sweet, weak
(Chapuis)
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NA
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(1S,2R,4R)-(-)-beta-Santalene
- Essentially no scent when freshly purified.
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NA
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(1R,2S,4S)-(+)-beta-Santalene
- Essentially no scent when freshly purified.
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NA
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(+)-(1'R,2'R,3'R,4'S,5'R)-(E)-alpha-Photosantalol
- Sandalwood, natural, pleasant, strong
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NA
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(-)-(1'S,2'S,3'S,4'R,5'S)-(E)-alpha-Photosantalol
- Woody, sandalwood, weak
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NA
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(-)-(1'S,2'R,4'R)-(E)-beta-Photosantalol
- Sandalwood, similar to (-)-(Z)-beta-Santalol
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NA
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(+)-(1'R,2'S,4'S)-(E)-beta-Photosantalol
- Odor not known
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NA
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Sandalwood Type Odorants from Campholenic
aldehyde
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(-)-(1'R)-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-1-al
- fragrance further possessing an aldehydic note,
reminiscent of citronellal, citrusy, spicy, recalling the
odor of the citronella leaves. As to its bottom note, it has
a character which is reminiscent of the odor of
3-(4-tert-butyl-1-phenyl)-2-methylpropanal, but with an even
greener connotation and a slightly orangy
aspect
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NA
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(+)-(1'S)-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-1-al
- a more metallic and aldehydic odor, recalling that of
trans-4-decenal, and the bottom note of which is more floral
and even stronger in the aqueous character. The use of this
latter compound to enhance the latter odor character in
perfumed compositions and articles is in fact preferred to
that of its (-)-(1'R)-enantiomer
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NA
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(-)-(1'R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-pentenenitrile
- a woody-citrus, fruity and slightly fatty odor prefered to
the (+)-(1'S)-isomer
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NA
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(+)-(1'S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-pentenenitrile
- not as prefered an odor as the
(-)-(1'R)-isomer
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NA
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(-)-(1'R,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-pentenenitrile - citrus, fruity and
fresh character accompanied by a sandalwood bottom
character
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NA
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(+)-(1'S,2s)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-pentenenitrile - odor not described
other than to say the (1'R)-isomers are
preferred
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(-)-(1'R,2S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-pentenenitrile - a sandalwood odor
wherein the desired fruity-citrus character of the
(-)-(1'R,2R)-isomer is no longer present
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NA
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(+)-(1'S,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-pentenenitrile - odor not described
other than to say the (1'R)-isomers are
preferred
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(-)-(1'R,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-ol - elegant and powerful sandalwood note
(prefered of the four isomers)
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NA
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(+)-(1'S,2S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-ol - odor is less rich in
the precious "lait de santal" type odor character present in
the (-)-(1'R,2R)- and (-)-(1'R,2S)- isomers
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NA
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(-)-(1'R,2S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-ol - sandalwood note is
not as powerful as the (-)-(1'R,2R)-isomer but is
accompanied of a more marked woody-cedar
character
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NA
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(+)-(1'S,2R)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-ol - odor is less rich in
the precious "lait de santal" type odor character present in
the (-)-(1'R,2R)- and (-)-(1'R,2S)- isomers
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NA
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(-)-(1'R,E)-3,3-dimethyl-5-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-2-ol
- develops a sandalwood note, the character of which is
strongly reminiscent of the typical milky odor of
sandalwood
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NA
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(+)-(1'S,E)-3,3-dimethyl-5-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)-4-penten-2-ol
- drier, more woody-cedar and less
milky than that of its (-)-(1'R,E)- isomer
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NA
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(+)-(1'S,2S,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
- develops a sandalwood note of remarkable strength, wherein
the typical milky character is represented at its best and
accompanied by a slightly animal note; prefered of four
possible isomers
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NA
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(-)-(1'R,2R,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
- weakest and less characteristic
sandalwood note than any of the other isomers
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NA
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(+)-(1'S,2R,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
- ranked in 3d place of 4 isomers for
its sandalwood odor
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NA
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(-)-(1'R,2S,E)-3,3-dimethyl-5-(2,2,3-trimethyl-3-cyclopenten-1-yl)-4-penten-2-ol
- weaker and less characteristic sandalwood note than the
(+)-(1'S,2S,E)-isomer but superior to the (+)-(1'S,2R,E)- or
(-)-(1'R,2R,E)- isomers
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NA
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(1'R,E)-(+)-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- fresh and strong sandalwood oil odor associated with green
trees
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51
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(1'S,E)-(-)-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- dry and weak sandalwood oil odor with a milky and floral
note
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424
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(1'R,Z)-(+)-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- Green, tomato, weak
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NA
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(1'S,Z)-(+)-2-Methyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- Woody, sandalwood, milk, very weak
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NA
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(1'R,E)-(-)-2-Ethyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- clean, bright and strong sandalwood oil odor with richness
and a woody note
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0.85
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(1'S,E)-(-)-2-Ethyl-4-(2,2,3-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- milky sandalwood oil odor with a cedar
character
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44
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(1'R,E)-(+)-2-Propyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- soft and warm sandalwood oil odor
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NA
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1'S,E)-(-)-2-Propyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- slightly sandalwood, weak
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NA
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(1'R,Z)-(-)-2-Propyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- green, vaguely fruity, woody
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NA
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(1'S,Z)-(+)-2-Propyl-4-(2',2',3'-trimethyl-cyclopent-3-enyl)-but-2-en-1-ol
- woody, very weak
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NA
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(1'R,E)-(-)-2,2-dimethyl-4-(2',2',3'-trimethylcyclopent-3-enyl)-but-3-en-1-ol
- Vaguely fruity, woody
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NA
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(1'S,E)-(+)-2,2-dimethyl-4-(2',2',3'-trimethylcyclopent-3-enyl)-but-3-en-1-ol
- sandalwood, fruity, dorisyl
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NA
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(-)-(1'R)-2-methyl-4-(2',2',3'-
trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-al - possesses an
unexpected odor in view of the prior knowledge regarding the
odor properties of campholenic aldehyde derivatives. It
develops a woody-sandalwood type odor note, slightly
aldehydic, which is more reminiscent of the cedar-pine odor
connotation than of the sandalwood type one, which note is
combined with a distinct marine, ozone character. The latter
is reinforced in the bottom note, which is strongly
ozone-marine-like, recalling the odor of seaweeds. In
addition, the odor of this compound has a good strength and
tenacity.
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NA
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(+)-(1'S)-2-methyl-4-(2',2',3'-trimethyl-3'-cyclopenten-1'-yl)
-4-penten-1-al - woody, sandalwood,
aldehydic, faintly aqueous
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NA
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(1'S,1''S,2'S,3''R,5''R)-Javanol
- sandalwood, creamy, warm, strong
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NA
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(1'R,1''R,2'R,3''S,5''S)-Javanol
- lactonic, lily of the valley
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NA
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(1'R,1''S,2'R,3''R,5''R)-Javanol
- lactonic, with a sandalwood aspect
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NA
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(1'S,1''R,2'S,3''S,5''S)-Javanol
- floral, rosy, milky, sandalwood
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NA
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(-)-axial-4-((1'R)-2,2,3-trimethylcyclopent-3-enyl)cyclohexanol
- not specific, vaguely sandalwood
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NA
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(+)-axial-4-((1'S)-2,2,3-trimethylcyclopent-3-enyl)cyclohexanol
- vaguely woody, slightly sandalwood
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NA
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(-)-equatorial-4-((1'R)-2,2,3-trimethylcyclopent-3-enyl)cyclohexanol
- woody, metallic
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NA
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(+)-equatorial-4-((1'S)-2,2,3-trimethylcyclopent-3-enyl)cyclohexanol
- without character
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NA
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(-)-axial-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol
- Weak, floral
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NA
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(+)-axial-1-Methyl-4-[(1'S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol
- Slightly sandalwood, weak
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NA
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(-)-equatorial-1-Methyl-4-[(1'R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol
- Weak
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NA
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(+)-equatorial-1-Methyl-4-[(1'S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexanol
- Slightly sandalwood
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NA
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(-)-(1:1
2E/Z)-2-{(4S)-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexylidene}ethanol
(1:1 mixture of E/Z isomers) - Without character
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NA
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(+)-(1:1
2E/Z)-2-{(4R)-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexylidene}ethanol
(1:1 mixture of E/Z isomers) - Green, cucumber, fatty,
mastic
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NA
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(-)-(2E/Z)-2-{(4S)-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexylidene}propan-1-ol
(1:1 mixture of E/Z isomers) - Woody, sandalwood, urine,
transpiration
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NA
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(+)-(2E/Z)-2-{(4R)-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexylidene}propan-1-ol
(1:1 mixture of E/Z isomers) - Woody, vaguely
sandalwood, weak
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NA
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(-)-{trans-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}methanol
- Woody, cedar
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NA
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(+)-{trans-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}methanol
- Woody
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NA
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(-)-(1RS)-1-{trans-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}ethanol
- Sandalwood, vague, weak
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NA
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(+)-(1RS)-1-{trans-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}ethanol
- Vague
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NA
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(-)-2-{trans-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}propan-2-ol
- Without olfactive character
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NA
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(+)-2-{trans-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]cyclohexyl}propan-2-ol
- Without character
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NA
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(1R,2'R,3'S)-Ebanol - weak, no
sandalwood odor relevance
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>100 (relative in series)
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|
(1S,2'S,3'R)-Ebanol - Powerful
sandalwood, more than 100X more powerful than its enantiomer
(based on relative GC sniff threshold) and more than 3X
stronger than (1R,2'S,3'R)-Ebanol
|
1 (relative in series)
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(1R,2'S,3'S)-Ebanol - Slight
sandalwood relevance, both enantiomers weak
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>100 (relative in series)
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(1S,2'R,3'R)-Ebanol - No
sandalwood relevance, both enantiomers weak
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>100 (relative in series)
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|
(1R,2'S,3'R)-Ebanol - Powerful
sandalwood, more than 33X more powerful than its enantiomer
and more than 3X weaker than (1S,2'S,3'R)-Ebanol
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3 (relative in series)
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(1S,2'R,3'S)-Ebanol - no
sandalwood relevance
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>100 (relative in series)
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|
(1R,2'R,3'R)-Ebanol - no
sandalwood relevance
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>100 (relative in series)
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|
(1S,2'S,3'S)-Ebanol - no
sandalwood relevance
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>100 (relative in series)
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|
(-)-(2R)-2-methyl-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol
- peculiar sandalwood's strongly excellent smell
|
18.7
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|
(+)-(2S)-2-methyl-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol
- weak and less preferred enantiomer
|
166.0
|
|
(+)-(2R)-2-methyl-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol
- peculiar sandalwood's strongly excellent smell
|
14.5
|
|
(-)-(2S)-2-methyl-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol
- weak and less preferred enantiomer
|
176.8
|
|
(+)-(3R,1'S)-HomoPolysantol
- Very clean but less intense sandalwood scent than the
(+)-(3S,1'S)-enantiomer, with woody, borneol and cashmeran
notes at the end (by GC-sniffing); On blotting paper strips
Lucta perfumers described it as: Top notes: smoky, tarry,
phenolic, guaiacol, woody on cedar, sandal and benjui notes.
Heart notes: sandalwood and burnt scents. Base note: weak
sandalwood odour.
|
NA
|
|
(-)-(3S,1'R)-HomoPolysantol
- Very clean sandalwood odour, with waxy note at end (by
GC-sniffing); On blotting paper strips Lucta perfumers
described it as: - Top notes: sandalwood, polysantol-type,
woody and dry. Heart notes: sandalwood and sandela very
intense. Base note: mild but clear sandalwood note. (Best of
the four diastereoisomers)
|
NA
|
|
(-)-(3R,1'R)-HomoPolysantol
- Sandalwood pure note, with a waxy note at the end (by
GC-sniffing); On blotting paper strips Lucta perfumers
described it as: Top notes: weak spicy, sandalwood, woody
and dry. Heart notes: weak spicy and sandalwood. Base note:
almost odourless.
|
NA
|
|
(+)-(3S,1'S)-HomoPolysantol
- Sandalwood pure note (by GC-sniffing); On blotting paper
strips Lucta perfumers described it as: Top notes: phenolic,
leather, styrax, sandalwood and woody. Heart notes: very
clean sandalwood and sandela scents. Base note: almost
odourless.
|
NA
|
|
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|
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Other Sandalwood Odorants
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|
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(1R,3R,1'S,2'R,4'S,6'S)-(+)-threo-trans-3-isocamphylcyclohexanol
- Strong, diffusive, and sandalwood-like odor; natural
sandalwood odor, but very strong and keen
|
0.2
|
|
(1S,3S,1'R,2'S,4'R,6'R)-(-)-threo-trans-3-isocamphylcyclohexanol
- weak, moldy and woody odor
|
200
|
|
(1S,3S,1'S,2'R,4'S,6'S)
(+)-erythro-trans-3-isocamphylcyclohexanol - sandalwood
like odor without moldy feeling, and it is sufficiently
diffusive
|
7
|
|
(1R,3R,1'R,2'S,4'R,6'R)-(-)-erythro-trans-3-isocamphylcyclohexanol
- strong, warm sandalwood odor
|
3
|
|
(-)-(1S,E)-5-(2',2-dimethyl-3'-methylene-1'-cyclohexyl)-3,3-dimethyl-4-penten-2-ol
- Woody, sandal, sweet note, reminiscent of the odor of the
bark and milk of the sandalwood tree.
|
NA
|
|
(+)-(1'R,E)-5-(2',2-dimethyl-3'-methylene-1'-cyclohexyl)-3,3-dimethyl-4-penten-2-ol
- Sandalwood odor, but distinctly different than the
(-)-(1S,E)-isomers
|
NA
|
|
(+)-(1S,3R,6R,8R)-8-tertbutylbicyclo[4.4.0]decan-3-ol
- strong, sandalwood like, warm, sweet and fatty, long
persisting,
|
NA
|
|
(-)-(1R,3S,6S,8S)-8-tertbutylbicyclo[4.4.0]decan-3-ol
- very weak, fatty, hardly perceptible, remote reminiscent
to animal notes.
|
NA
|
|
(2S,3R,4E)-3-methyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- very strong, sandal(wood), animalic
|
5
|
|
(2R,3S,4E)-3-methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- weak, woody
|
168
|
|
(2R,3S,4E)-3-methyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- sandal(wood), animalic
|
70
|
|
(2S,3R,4E)-3-methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- woody
|
72
|
|
(2R,3R,4E)-3-methyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- sandal(wood), floral
|
137
|
|
(2S,3S,4E)-3-methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- very weak floral
|
159
|
|
(2S,3S,4E)-3-methyl-4-[(1R,2R,6R,7R)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- strong sandal(wood), floral
|
46
|
|
(2R,3R,4E)-3-methyl-4-[(1S,2S,6S,7S)-tricyclo[5.2.1.02,6]dec-4-en-8-ylidene]butan-2-ol
- weak floral
|
204
|
