Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 2-methyl-4-[2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ols

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Photo by permission of M. Roudintska - Art & Parfum

(-)-(2R)-2-methyl-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol - peculiar sandalwood's strongly excellent smell

Odor Threshold = 18.7 ppb

Ref: AIDA TAKASHI; MATSUDA HIROYUKI; YAMAMOTO TAKESHI, (2R)-2-METHYL-4-(2,2,3-TRIMETHYL-3-CYCLOPENTEN-1-YL)-1-BUTANOL, ITS PRODUCTION AND USE, Japanese Patent No. 8268940, October 15, 1996

(+)-(2S)-2-methyl-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol - weak and less preferred enantiomer

Odor Threshold = 166.0 ppb

Ref: AIDA TAKASHI; MATSUDA HIROYUKI; YAMAMOTO TAKESHI, (2R)-2-METHYL-4-(2,2,3-TRIMETHYL-3-CYCLOPENTEN-1-YL)-1-BUTANOL, ITS PRODUCTION AND USE, Japanese Patent No. 8268940, October 15, 1996

(+)-(2R)-2-methyl-4-[(1S)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol - peculiar sandalwood's strongly excellent smell

Odor Threshold = 14.5 ppb

Ref: AIDA TAKASHI; MATSUDA HIROYUKI; YAMAMOTO TAKESHI, (2R)-2-METHYL-4-(2,2,3-TRIMETHYL-3-CYCLOPENTEN-1-YL)-1-BUTANOL, ITS PRODUCTION AND USE, Japanese Patent No. 8268940, October 15, 1996

(-)-(2S)-2-methyl-4-[(1R)-2,2,3-trimethylcyclopent-3-en-1-yl]butan-1-ol - weak and less preferred enantiomer

Odor Threshold = 176.8 ppb

Ref: AIDA TAKASHI; MATSUDA HIROYUKI; YAMAMOTO TAKESHI, (2R)-2-METHYL-4-(2,2,3-TRIMETHYL-3-CYCLOPENTEN-1-YL)-1-BUTANOL, ITS PRODUCTION AND USE, Japanese Patent No. 8268940, October 15, 1996

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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