Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 1-(2,2,6-Trimethylcyclohexyl)-pentan-3-ones

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Photo by permission of M. Roudintska - Art & Parfum

(1'R,6'S)-(+)-1-(2',2',6'-Trimethyl-cyclohexyl)-pentan-3-one - Woody, irone, weak

Ref: Chapuis, Christian; Brauchli, Robert; Preparation of Optically Active Flowery and Woody-Like Odorant Ketones via Corey-Chaykovsky Oxiranylation: Irones and Analogues, Helv.Chim.Acta, 1993, 76: 2070-2088; Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enantioselective perception of chiral odorants, Tetrahedron: Asymmetry, 14, 1–42 (2003)

(1'S,6'R)-(-)-1-(2',2',6'-Trimethyl-cyclohexyl)-pentan-3-one - Amber, woody, saffron

Ref: Chapuis, Christian; Brauchli, Robert; Preparation of Optically Active Flowery and Woody-Like Odorant Ketones via Corey-Chaykovsky Oxiranylation: Irones and Analogues, Helv.Chim.Acta, 1993, 76: 2070-2088; Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enantioselective perception of chiral odorants, Tetrahedron: Asymmetry, 14, 1–42 (2003)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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