TheNirvanolides

Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Nirvanolides^®

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Photo by permission of M. Roudintska - Art & Parfum

(12R,9Z)- Nirvanolide^® - intense musky, fruity, powdery odor with lactonic nuances

Odor threshold = 0.05 ng/liter in air

= (12R,9Z)-(-)-12-methyl-14-tetradec-9-enolide

Ref: Philip Kraft & Georg Frater, Enantioselectivity of the musk odor sensation, Chirality, 13, 388-394 (2001)

Nirvanolide^® is a trademark of Givaudan

(12S,9Z)- Nirvanolide^® - odorless

= (12S,9Z)-12-methyl-14-tetradec-9-enolide

Ref: Philip Kraft & Georg Frater, Enantioselectivity of the musk odor sensation, Chirality, 13, 388-394 (2001)

Nirvanolide^® is a trademark of Givaudan

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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