Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Myrtenal diethyl acetals

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Photo by permission of M. Roudintska - Art & Parfum

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(1S,5R)-(+)-Myrtenal diethyl acetal - Probability levels of significant differentiation between the enantiomer pairs - >25.0% with 37 untrained panelists; >90.0% with 29 expert panelists; overall >98.0% (all 66 panelists).

No comments on the odor of the enantiomers was provided in Theimer's paper.

= (1S,5R)-2-(diethoxymethyl)-6,6-dimethylbicyclo[3.1.1]hept-2-ene

Ref: E.T. Theimer and Mina R. McDaniel, Odor and optical activity, J. Soc. Cosmet. Chem. 22, 5-26 (1971)

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(1R,5S)-(+)-Myrtenal diethyl acetal - Probability levels of significant differentiation between the enantiomer pairs - >25.0% with 37 untrained panelists; >90.0% with 29 expert panelists; overall >98.0% (all 66 panelists).

No comments on the odor of the enantiomers was provided in Theimer's paper.

= (1R,5S)-2-(diethoxymethyl)-6,6-dimethylbicyclo[3.1.1]hept-2-ene

Ref: E.T. Theimer and Mina R. McDaniel, Odor and optical activity, J. Soc. Cosmet. Chem. 22, 5-26 (1971)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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