Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Methyl 3-hydroxyhexanoates

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Photo by permission of M. Roudintska - Art & Parfum

Methyl (R)-(-)-3-hydroxyhexanoate - sweet, woody, fruity.

Odor threshold: 2.1 ng/L in air; 3.76 ppm in water

The racemate is described as sweet woody, overipe ripe fruity estry, pineapple, juicy, oily

Ref: Andrea Buettner and Peter Schieberle, Evaluation of Key Aroma Compounds in Hand-Squeezed Grapefruit Juice (Citrus paradisi Macfayden) by Quantitation and Flavor Reconstitution Experiments, J. Agric. Food Chem. 2001, 49, 1358-1363; see pineapple hydroxyhexanoate (Good Scents Co.)

Methyl (S)-(+)-3-hydroxyhexanoate - weak and aldehyde-like.

Odor threshold: 4380 ng/L in air

Ref: Andrea Buettner and Peter Schieberle, Evaluation of Key Aroma Compounds in Hand-Squeezed Grapefruit Juice (Citrus paradisi Macfayden) by Quantitation and Flavor Reconstitution Experiments, J. Agric. Food Chem. 2001, 49, 1358-1363

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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