Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 2-Ethylhexanols

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Photo by permission of M. Roudintska - Art & Parfum

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(-)-(2R)-2-ethylhexanol - Odor description: heavy, earthy, and slightly floral

= (-)-(2R)-2-ethylhexan-1-ol

Ref: Klaus Rettinger, Christian Burschka, Peter Scheeben, Heike Fuchs and Armin Mosandl, Chiral 2-alkylbranched acids, esters and alcohols. Preparation and stereospecific flavour evaluation, Tetrahedron: Asymmetry 1991, 2, 965 as reviewd in Elisabetta Brenna, Claudio Fuganti, Francesco G. Gatti, and Stefano Serra, Biocatalytic Methods for the Synthesis of Enantioenriched Odor Active Compounds, Chem. Rev., Article ASAP, DOI: 10.1021/cr100289r, Publication Date (Web): May 20, 2011

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(+)-(2S)-2-ethylhexanol - Odor description: a light, sweet floral fragrance

= (+)-(2S)-2-ethylhexan-1-ol

Ref: Klaus Rettinger, Christian Burschka, Peter Scheeben, Heike Fuchs and Armin Mosandl, Chiral 2-alkylbranched acids, esters and alcohols. Preparation and stereospecific flavour evaluation, Tetrahedron: Asymmetry 1991, 2, 965 as reviewd in Elisabetta Brenna, Claudio Fuganti, Francesco G. Gatti, and Stefano Serra, Biocatalytic Methods for the Synthesis of Enantioenriched Odor Active Compounds, Chem. Rev., Article ASAP, DOI: 10.1021/cr100289r, Publication Date (Web): May 20, 2011

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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