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-doremox.gif)
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(2R,4S)-cis-Doremox®
(ee=92%) - rose oxide, diphenyl oxide, metallic,
slightly plastic
=
(2R,4S)-4-methyl-2-phenyltetrahydro-2H-pyran
Ref:
Elisabetta Brenna, Claudio Fuganti, Sabrina
Ronzani, and Stefano Serra, Biocatalyzed
preparation of the optically enriched
stereoisomers of
4-methyl-2-phenyl-tetrahydro-2H-pyran
(Doremox®), Can. J. Chem., 80(6): 714-723
(2002); Elisabetta Brenna, Claudio Fuganti and
Stefano Serra, Enantioselective perception of
chiral odorants, Tetrahedron: Asymmetry, 14,
1–42 (2003)
Doremox®
is a registered trademark of Firmenich
SA
|
|
-doremox.gif)
|
(2S,4R)-cis-Doremox®
(ee=80%) - rose oxide, powerful, nice. The
(2S,4R)-cis-enantiomer is, thus, the nicest and
the most powerful isomer of the series. This
stereoisomer, incidentally, has the same
absolute configuration of the most appreciated
of rose oxide isomers, i.e.
(2S,4R)-cis-rose
oxide
=
(2S,4R)-4-methyl-2-phenyltetrahydro-2H-pyran
Ref:
Elisabetta Brenna, Claudio Fuganti, Sabrina
Ronzani, and Stefano Serra, Biocatalyzed
preparation of the optically enriched
stereoisomers of
4-methyl-2-phenyl-tetrahydro-2H-pyran
(Doremox®), Can. J. Chem., 80(6): 714-723
(2002); Elisabetta Brenna, Claudio Fuganti and
Stefano Serra, Enantioselective perception of
chiral odorants, Tetrahedron: Asymmetry, 14,
1–42 (2003)
Doremox®
is a registered trademark of Firmenich
SA
|
|
|
-doremox.gif)
|
(2R,4R)-trans-Doremox®
(ee=50%) - rosy, rose oxide, metallic, off
note
=
(2R,4R)-4-methyl-2-phenyltetrahydro-2H-pyran
Ref:
Elisabetta Brenna, Claudio Fuganti, Sabrina
Ronzani, and Stefano Serra, Biocatalyzed
preparation of the optically enriched
stereoisomers of
4-methyl-2-phenyl-tetrahydro-2H-pyran
(Doremox®), Can. J. Chem., 80(6): 714-723
(2002); Elisabetta Brenna, Claudio Fuganti and
Stefano Serra, Enantioselective perception of
chiral odorants, Tetrahedron: Asymmetry, 14,
1–42 (2003)
Doremox®
is a registered trademark of Firmenich
SA
|
|
-doremox.gif)
(2S,4S)-trans-Doremox®
(ee=72%) - weak, rosy, plastic, citronellol, a
rose oxide note is also present.
=
(2S,4S)-4-methyl-2-phenyltetrahydro-2H-pyran
Ref:
Elisabetta Brenna, Claudio Fuganti, Sabrina
Ronzani, and Stefano Serra, Biocatalyzed
preparation of the optically enriched
stereoisomers of
4-methyl-2-phenyl-tetrahydro-2H-pyran
(Doremox®), Can. J. Chem., 80(6): 714-723
(2002); Elisabetta Brenna, Claudio Fuganti and
Stefano Serra, Enantioselective perception of
chiral odorants, Tetrahedron: Asymmetry, 14,
1–42 (2003)
Doremox®
is a registered trademark of Firmenich
SA
|
|
