Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Diospenols

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Photo by permission of M. Roudintska - Art & Parfum

(4R)-(-)-Disophenol - woody, camphor-like, menthofuran, minty, isoeugenol, clove, bucchu, menthone/pulegone, dusty, jasmone-like

= (6R)-(-)-2-hydroxy-6-isopropyl-3-methylcyclohex-2-en-1-one

Ref: G. E. Krammer, H-J. Bertram, M. Guntert, S Lambrecht, H. Sommer, P Werkhoff, J. Kaulen, New Sulfur-Bearing Compounds in Buchu Leaf Oil, in Flavour Science: Recent Developments, A. J. Taylor, D. S. Mottram, Editors, Royal Society of Chemistry (1997)

(4S)-(+)-Disophenol - not as strong as the (R)-enantiomer. Characterised as woody, camphor-like, dusty, medicinal, isoeugenol, cis-jasmone-like, terpene-like

= (6S)-(+)-2-hydroxy-6-isopropyl-3-methylcyclohex-2-en-1-one

Ref: G. E. Krammer, H-J. Bertram, M. Guntert, S Lambrecht, H. Sommer, P Werkhoff, J. Kaulen, New Sulfur-Bearing Compounds in Buchu Leaf Oil, in Flavour Science: Recent Developments, A. J. Taylor, D. S. Mottram, Editors, Royal Society of Chemistry (1997)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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