Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Cassyranes

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Photo by permission of M. Roudintska - Art & Parfum

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(+)-(2S,5S)-Cassyrane - Odor description: Fruity, cassis, raspberry-type odor with slight herbaceous aspects recalling rosemary.

Odor threshold: 40 ng/L air.

= (+)-(2S,5S)-2-tert-Butyl-5-methyl-2-propyl-2,5-dihydrofuran

Ref: Mouhib, H., Stahl, W., Lüthy, M., Büchel, M. and Kraft, P. (2011), Cassis Odor through Microwave Eyes: Olfactory Properties and Gas-Phase Structures of all the Cassyrane Stereoisomers and its Dihydro Derivatives. Angewandte Chemie International Edition, 50: 5576–5580

Cassyrane is a registered trademark of Givaudan S.A.

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(-)-(2R,5R)-Cassyrane - Odor description: Agrestic, rosemary, terpenic-piney odor with fruity, eucalyptus-like and slightly resinous nuances.

Odor threshold: 136 ng/L air.

= (-)-(2R,5R)-2-tert-Butyl-5-methyl-2-propyl-2,5-dihydrofuran

Ref: Mouhib, H., Stahl, W., Lüthy, M., Büchel, M. and Kraft, P. (2011), Cassis Odor through Microwave Eyes: Olfactory Properties and Gas-Phase Structures of all the Cassyrane Stereoisomers and its Dihydro Derivatives. Angewandte Chemie International Edition, 50: 5576–5580

Cassyrane is a registered trademark of Givaudan S.A.

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(+)-(2R,5S)-Cassyrane - Odor description: Fruity-juicy cassis odor with slightly agrestic aspects and nuances of eucalyptus seed and dried leaves.

Odor threshold: 40 ng/L air.

= (+)-(2R,5S)-2-tert-Butyl-5-methyl-2-propyl-2,5-dihydrofuran

Ref: Mouhib, H., Stahl, W., Lüthy, M., Büchel, M. and Kraft, P. (2011), Cassis Odor through Microwave Eyes: Olfactory Properties and Gas-Phase Structures of all the Cassyrane Stereoisomers and its Dihydro Derivatives. Angewandte Chemie International Edition, 50: 5576–5580

Cassyrane is a registered trademark of Givaudan S.A.

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(-)-(2S,5R)-Cassyrane - Odor description: Agrestic odor in the direction of rosemary and eucalyptus with fruity, straw-like aspects, and slightly medicinal, terpenic, dry woody-resinous facets.

Odor threshold: 0.55 ng/L air.

= (-)-(2S,5R)-2-tert-Butyl-5-methyl-2-propyl-2,5-dihydrofuran

Ref: Mouhib, H., Stahl, W., Lüthy, M., Büchel, M. and Kraft, P. (2011), Cassis Odor through Microwave Eyes: Olfactory Properties and Gas-Phase Structures of all the Cassyrane Stereoisomers and its Dihydro Derivatives. Angewandte Chemie International Edition, 50: 5576–5580

Cassyrane is a registered trademark of Givaudan S.A.

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Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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