Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The Carveols

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Photo by permission of M. Roudintska - Art & Parfum

(+)-(2R,4S)-carveol - musty (Friedman, et. al.); Animal-musk indolic tone with citrus juice notes (Ishihara, et. al)

= (+)-(1R,5S)-5-isopropenyl-2-methylcyclohex-2-en-1-ol

Ref: Ref: L. Friedman & J. G. Miller, Odor Incongruity and Chirality, Science, Vol. 172, 1044-1046 (1971); Masakazu Ishihara, Hideki Nakamoto, Akira Matsuyama, Tetsuo Kawai, Takeshi Yonetani, Agent For Improving Quality of Perfume, Japanese Patent Publication No. 10219272 (August 18, 1998)

Note - the odor descriptions by Ishihara et. al. were derived by computer translation from the Japanese and may vary slightly from the original language.

(-)-(2S,4R)-carveol - minty (Friedman, et. al.); light, soft spearmint, minty (Ishihara, et. al)

= (-)-(1S,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-ol

Ref: L. Friedman & J. G. Miller, Odor Incongruity and Chirality, Science, Vol. 172, 1044-1046 (1971); Masakazu Ishihara, Hideki Nakamoto, Akira Matsuyama, Tetsuo Kawai, Takeshi Yonetani, Agent For Improving Quality of Perfume, Japanese Patent Publication No. 10219272 (August 18, 1998)

Note - the odor descriptions by Ishihara et. al. were derived by computer translation from the Japanese and may vary slightly from the original language.

(+)-(2S,4S)-carveol - Spicy, peppermint, minty

= (+)-(1S,5S)-5-isopropenyl-2-methylcyclohex-2-en-1-ol

Ref: Masakazu Ishihara, Hideki Nakamoto, Akira Matsuyama, Tetsuo Kawai, Takeshi Yonetani, Agent For Improving Quality of Perfume, Japanese Patent Publication No. 10219272 (August 18, 1998)

Note - the odor descriptions by Ishihara et. al. were derived by computer translation from the Japanese and may vary slightly from the original language.

(-)-(2S,4R)-carveol - Heavy, spearmint, minty

= (-)-(1R,5R)-5-isopropenyl-2-methylcyclohex-2-en-1-ol

Ref: Masakazu Ishihara, Hideki Nakamoto, Akira Matsuyama, Tetsuo Kawai, Takeshi Yonetani, Agent For Improving Quality of Perfume, Japanese Patent Publication No. 10219272 (August 18, 1998)

Note - the odor descriptions by Ishihara et. al. were derived by computer translation from the Japanese and may vary slightly from the original language.

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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