Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 4,8-Dimethylnon-7-en-4-olides

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Photo by permission of M. Roudintska - Art & Parfum

(-)-(S)-4,8-dimethylnon-7-en-4-olide - fresh fruity lactone odour with peach and/or pear-like nuances It also has green and floral notes.

Threshold: 0.65 ppb (in water)

= (-)-(5S)-5-methyl-5-(4-methylpent-3-enyl)dihydrofuran-2(3H)-one

Ref: Taro Kitaura, Hirokatsu Endo, Hideki Nakamoto, Masakazu Ishihara, Tetsuo Kawai, Junzo Nokami, Isolation and synthesis of a new natural lactone in apple juice (Malus × domestica var. Orin), Flavour and Fragrance Journal, Volume 19, Issue 3 , Pages 221 - 224 (2004)

(+)-(R)-4,8-dimethylnon-7-en-4-olide - an oily and heavy lactone odour which is expressed rather milky and coconut-like.

Threshold: 0.16 ppb (in water)

= (+)-(5R)-5-methyl-5-(4-methylpent-3-enyl)dihydrofuran-2(3H)-one

Ref: Taro Kitaura, Hirokatsu Endo, Hideki Nakamoto, Masakazu Ishihara, Tetsuo Kawai, Junzo Nokami, Isolation and synthesis of a new natural lactone in apple juice (Malus × domestica var. Orin), Flavour and Fragrance Journal, Volume 19, Issue 3 , Pages 221 - 224 (2004)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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