Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 2-Methyl-4-phenyl-[1,3]dioxolanes

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Photo by permission of M. Roudintska - Art & Parfum

(2R,4S)-cis-2-Methyl-4-phenyl-[1,3]dioxolane - Strong, clear, indole, rose-jasmine, the strongest- and best-smelling enantiomer

Threshold = 125 µg/liter of air

Ref: Wilhelm Pickenhagen & Dietmar Schatkowski, 2-methyl-4-pheny1-1,3-dioxolane, United States Patent Application 20010004457 (June 21, 2001)

(2S,4R)-cis-2-Methyl-4-phenyl-[1,3]dioxolane - Styrene, indole, skatole, hyacinths

Threshold = 384 µg/liter of air

Ref: Wilhelm Pickenhagen & Dietmar Schatkowski, 2-methyl-4-pheny1-1,3-dioxolane, United States Patent Application 20010004457 (June 21, 2001)

(2S,4S)-trans-2-Methyl-4-phenyl-[1,3]dioxolane - Floral, woody, diphenyl ether, rose, animal, chocolate note

Threshold = 384 µg/liter of air

Ref: Wilhelm Pickenhagen & Dietmar Schatkowski, 2-methyl-4-pheny1-1,3-dioxolane, United States Patent Application 20010004457 (June 21, 2001)

(2R,4R)-trans-2-Methyl-4-phenyl-[1,3]dioxolane - Floral, lilac, woody, orange liquid, chocolate note

Threshold = 589 µg/liter of air

Ref: Wilhelm Pickenhagen & Dietmar Schatkowski, 2-methyl-4-pheny1-1,3-dioxolane, United States Patent Application 20010004457 (June 21, 2001)

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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Copyright 2001 - Leffingwell & Associates