Chirality & Odour Perception
John C. Leffingwell, Ph.D.

The 2,4,6-trimethyl-4-[(E)-2-phenylvinyl]-1,3-dioxanes

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Photo by permission of M. Roudintska - Art & Parfum

(+)-(2R,4S,6R)-2,4,6-trimethyl-4-[(E)-2-phenylvinyl]-1,3-dioxane - (ee = 92%): animalic, woody, green, cumin oil, not clean, after 24 hours dry-down, unpleasant, cuminic–dirty–animalic.

Ref: Agnese Abate, Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enzyme-mediated synthesis of new 1,3-dioxane odorants related to Floropal®, Flavour Fragr. J. 2004; 19: 382–393

(-)-(2S,4R,6S)-2,4,6-trimethyl-4-[(E)-2-phenylvinyl]-1,3-dioxane - (ee = 79%): green, vegetable note, not clean, after 24 hours unpleasant cuminic.

Ref: Agnese Abate, Elisabetta Brenna, Claudio Fuganti and Stefano Serra, Enzyme-mediated synthesis of new 1,3-dioxane odorants related to Floropal®, Flavour Fragr. J. 2004; 19: 382–393

Cyclic Terpenoid Odorants

Bicyclic Terpenoid Odorants

Acyclic Terpenoid Odorants

Ionones, Irones, Damascones & Structurally Related Odorants

Acyclics (Alcohols, Esters, Acids, Aldehydes)

Lactones

Sesquiterpenoid Related Odorants

Steroid Urine Type Odorants

Sandalwood Type Odorants

Musk Odorants

Miscellaneous

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